The region (ital. Lazio) with the capital Rome is located in the centre of Italy at the "knee" of the boot. It extends 320 kilometres to the west along the coast of the Tyrrhenian Sea. All other six central regions border on Lazio. Starting from the north, these are Tuscany, Umbria, Marche (only a short stretch), Abruzzo, Molise and Campania. Even in ancient times there was extensive viticulture and a distinct wine culture here. The area provided food and drink for the capital of the Roman Empire. In ancient times, it was mainly full-bodied, amber-coloured, spicy white wines that came from here. For many centuries Rome's poets praised the wines of Lazio, especially the predecessor of Frascati. At the nearby papal court, wine played an important role in the Middle Ages. Pope Paul III. (1468-1549) outlawed French wine and had his wine chamberlain Sante Lancerio compile an overview of the Italian wines of the time.
The vineyards cover about 19,500 hectares. The climate is dry and hot on the coast and becomes increasingly cooler and humid inland. Except in the Apennines with the highest peak Monte Terminillo at 2,216 metres, are cultivated almost everywhere. To 80% white wines are produced, which thrive particularly well on the often volcanic soils. It is noteworthy that within the administrative borders of the city of Rome there are also extensive vineyards. More than a third of the wine production is carried out by winegrowers' cooperatives. The numerous small winegrowers cultivate on average only half a hectare of vineyards and deliver most of their grapes to the large cooperative wineries.