Canton with the capital of the same name in French-speaking Switzerland in the south-west of the country. It is also one of the six Swiss wine regions. The vineyards on mostly clay, limestone and gravel-rich soils cover 1,340 hectares of vines around the town at the south-western end of Lac Léman (Lake Geneva) and between the right bank of the Rhône and the French border (the so-called Mandement). Over half of the vineyards are planted with the Chasselas variety (here with the protected name Perlan). Other white wine varieties include Müller-Thurgau, Aligoté, Chardonnay, Freisamer, Kerner, Pinot Blanc, Sauvignon Blanc and Sémillon. The dominant red wine variety is Pinot Noir with one third of the area, others are Cabernet Sauvignon, Gamaret, Garanoir, Merlot and Syrah.

Geneva was the first canton to enact laws for the production of wines with controlled origin (AOC) in 1988. The classified AOC communes are Bardonnex, Céligny, Choulex, Choully, Collex-Bossy, Cologny, Dardagny, Hermance, Lully, Jussy, Peissy, Russin and Satigny (the largest wine-growing commune in Switzerland with just under 500 hectares). Under the name "Cave de Genève", around one hundred winegrowers produce around a quarter of all Geneva wines on around 400 hectares of vineyards. Well-known producers include Domaine des Balisiers, Florian Barthassat, Dupraz, Domaine Grand'Cour, Domaine des Molards, Domaine du Paradis and Ramu.